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The resulting cyclicpeptides are cell permeable and have improved proteolytic stability.
2
Peptide thioesters serve as fundamental building blocks for the synthesis of proteins and cyclicpeptides.
3
Measurements made in the presence of verapamil showed that the cyclicpeptides experienced a ca.
4
However, the MSDIN gene family encoding for these cyclicpeptides in A. fuligineoides has not been systematically studied.
5
However, their applications against intracellular targets have been limited, because cyclicpeptides are generally impermeable to the cell membrane.
1
The aminoglycosides and cyclicpolypeptides are essential drugs in the treatment of multidrug-resistant tuberculosis, underscoring the need for accurate and reproducible drug susceptibility testing (DST).
Usage of cyclic peptide in inglês
1
Also a specific conformation is required for the cyclicpeptide when bound to the protein.
2
The synthesis of the first members of a new class of cyclicpeptide-containing hemicryptophanes is described.
3
Data of the distribution of AZD2820, a therapeutic cyclicpeptide, are related to corresponding QWBA data.
4
We developed this cyclicpeptide inhibitor through an epitope-targeted library screening process and validated its binding to proMMP2.
5
Amanita fuligineoides, a lethal mushroom discovered in China, contains abundant cyclicpeptide toxins that can cause fatal poisoning.
6
This D-amino acid cyclicpeptide did not adopt a conformation homologous to the NGF C-D loop and was inactive.
7
Using a human melanoma cell line, we demonstrated the cyclicpeptide's ability to modulate cellular MMP2 activities and inhibit cell migration.
8
The resulting cyclicpeptides are cell permeable and have improved proteolytic stability.
9
Cyclicpeptides have great potential as therapeutic agents and research tools.
10
Cyclicpeptides have been a rich source of biologically active molecules.
11
Peptide thioesters serve as fundamental building blocks for the synthesis of proteins and cyclicpeptides.
12
Measurements made in the presence of verapamil showed that the cyclicpeptides experienced a ca.
13
Cyclicpeptides (CPs) are an exciting class of molecules with a variety of applications.
14
Cyclicpeptide natural products have evolved to exploit diverse protein targets, many of which control essential cellular processes.
15
However, the MSDIN gene family encoding for these cyclicpeptides in A. fuligineoides has not been systematically studied.
16
Cyclicpeptides have great potential as therapeutic agents and research tools but are generally impermeable to the cell membrane.